Borane → N-[2-(4-(2-Hydroxyethoxy)phenyl)-1-methylethyl]-2-(2-chloro-thiazol-4-yl)morpholine

HRID 2128311Notes

Reaction equation

HRID 2128311 reaction equation
[BH3:33].[C:1](=[O:2])([O:3][CH3:4])[CH2:5][O:6][c:7]1[cH:8][cH:9][c:10]([CH2:13][CH:14]([CH3:15])[N:16]2[CH2:17][CH:18]([c:22]3[n:23][c:24]([Cl:27])[s:25][cH:26]3)[O:19][CH2:20][CH2:21]2)[cH:11][cH:12]1.[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1>>[CH2:1]([OH:2])[CH2:5][O:6][c:7]1[cH:8][cH:9][c:10]([CH2:13][CH:14]([CH3:15])[N:16]2[CH2:17][CH:18]([c:22]3[n:23][c:24]([Cl:27])[s:25][cH:26]3)[O:19][CH2:20][CH2:21]2)[cH:11][cH:12]1

Participants

4

Reactant 3

HCID 6331BoraneHCID 8028TetrahydrofuranHCID 19974190N-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-2-(2-chloro-thiazol-4-yl)morpholine

Product 1

HCID 19974191N-[2-(4-(2-Hydroxyethoxy)phenyl)-1-methylethyl]-2-(2-chloro-thiazol-4-yl)morpholine

Sources & evidence

ORD record
ord-9ba58c81fe874bcc8aeb84047cc64eed
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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