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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2128681Generated: October 31, 2026

Tetrahydrofuran → 3-(Pyrimidin-2-yl)-2,2-bis(3-(trifluoromethoxy)phenyl)propanoic acid

https://huagongshe.com/reaction/2128681

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant2-(Bromomethyl)pyrimidineHCID 22032757—
Reactant2,2-Bis(3-(trifluoromethoxy)phenyl)acetic acidHCID 59458359—
ReactantButyllithiumHCID 178418339—
Product3-(Pyrimidin-2-yl)-2,2-bis(3-(trifluoromethoxy)phenyl)propanoic acidHCID 59459035—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-6b1e513efaff493a9b7f881df0048a38
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)