1-(2-Fluorophenyl)piperazine → 1-(3-(1-tert-butyl-5-(thiophene-2-yl)-1H-pyrazol-3-yl)propyl)-4-(2-fluorophenyl)piperazine
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[n:5]1[n:6][c:7]([CH2:15][CH2:16][CH:17]=[O:18])[cH:8][c:9]1-[c:10]1[s:11][cH:12][cH:13][cH:14]1.[CH:32]([N:33]([CH2:34][CH3:35])[CH:36]([CH3:37])[CH3:38])([CH3:39])[CH3:40].[F:19][c:20]1[c:21]([N:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[cH:22][cH:23][cH:24][cH:25]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[n:5]1[n:6][c:7]([CH2:15][CH2:16][CH2:17][N:29]2[CH2:28][CH2:27][N:26]([c:21]3[c:20]([F:19])[cH:25][cH:24][cH:23][cH:22]3)[CH2:31][CH2:30]2)[cH:8][c:9]1-[c:10]1[s:11][cH:12][cH:13][cH:14]1Participants
4
Sources & evidence
- ORD record
- ord-e91f3be0eb2444f3a69ec0c3f4076995
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…