Diisopropylamine → 2-(2-Fluoropyridin-4-yl)-1-[3-(trifluoromethyl)phenyl]ethanone
Reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:21][O:22][N:23]([C:24]([c:25]1[cH:26][c:27]([C:31]([F:32])([F:33])[F:34])[cH:28][cH:29][cH:30]1)=[O:35])[CH3:36].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[F:13][c:14]1[n:15][cH:16][cH:17][c:18]([CH3:20])[cH:19]1>>[F:13][c:14]1[n:15][cH:16][cH:17][c:18]([CH2:20][C:24]([c:25]2[cH:26][c:27]([C:31]([F:32])([F:33])[F:34])[cH:28][cH:29][cH:30]2)=[O:35])[cH:19]1Participants
6
Sources & evidence
- ORD record
- ord-2777b34329494ec986a77c4c796631e9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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