Hydrochloric Acid → 1-[2-(4-Aminopiperidin-1-yl)ethyl]-2-oxo-1,2-dihydroquinoline-7-carbonitrile

HRID 2129038Notes

Reaction equation

HRID 2129038 reaction equation
[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]2[cH:7][cH:8][c:9](=[O:29])[n:10]([CH2:13][CH2:14][N:15]3[CH2:16][CH2:17][CH:18]([NH:21][C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:19][CH2:20]3)[c:11]2[cH:12]1.[CH2:42]1[O:43][CH2:44][CH2:45][O:46][CH2:47]1.[CH3:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[CH:38]([Cl:39])([Cl:40])[Cl:41].[ClH:30]>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]2[cH:7][cH:8][c:9](=[O:29])[n:10]([CH2:13][CH2:14][N:15]3[CH2:16][CH2:17][CH:18]([NH2:21])[CH2:19][CH2:20]3)[c:11]2[cH:12]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 1140TolueneHCID 6212ChloroformHCID 312751,4-DioxaneHCID 60200429tert-butyl 1-(2-(7-cyano-2-oxoquinolin-1(2H)-yl)ethyl)piperidin-4-ylcarbamate

Product 1

HCID 602009201-[2-(4-Aminopiperidin-1-yl)ethyl]-2-oxo-1,2-dihydroquinoline-7-carbonitrile

Sources & evidence

ORD record
ord-38d338d7982a4d61a55a42ed017b6a59
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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