Water → 2-[5-(3-Amino-5-methylphenyl)-1,3-thiazol-2-yl]-1,1,1-trifluoropropan-2-ol
Reaction equation
[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:13][c:14]1[cH:15][c:16]([NH2:17])[cH:18][c:19](-[c:21]2[cH:22][n:23][cH:24][s:25]2)[cH:20]1.[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[Cl:39][CH2:40][Cl:41].[F:26][C:27]([C:28](=[O:29])[CH3:30])([F:31])[F:32].[OH2:38]>>[CH3:13][c:14]1[cH:15][c:16]([NH2:17])[cH:18][c:19](-[c:21]2[cH:22][n:23][c:24]([C:28]([C:27]([F:26])([F:31])[F:32])([OH:29])[CH3:30])[s:25]2)[cH:20]1Participants
8
Sources & evidence
- ORD record
- ord-6c8093d4571f4b349e79fefb01616582
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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