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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2129484Generated: October 28, 2026

Chlorotrimethylsilane → tert-Butyl 3-(pyrimidin-2-ylmethyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/2129484

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorotrimethylsilaneHCID 6397—
Reactant1,2-DibromoethaneHCID 7839—
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantPalladiumHCID 23938—
Reactant2-ChloropyrimidineHCID 74404—
ReactantTri-o-tolylphosphineHCID 80271—
ReactantDibenzylidene acetoneHCID 95417—
ReactantTert-butyl 3-(iodomethyl)piperidine-1-carboxylateHCID 20716152—
Producttert-Butyl 3-(pyrimidin-2-ylmethyl)piperidine-1-carboxylateHCID 57732184—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-90c4e52443104cb68ffe506edfd4e34b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)