N-methyl-2-pyrrolidone → 7-(1,4'-bipiperidin-1'-yl)-4-({3-chloro-4-[(1-methyl-1H-imidazole-2-yl)thio]phenyl}amino)-6-methoxyquinoline-3-carbonitrile
Reaction equation
[CH3:43][N:44]1[CH2:45][CH2:46][CH2:47][C:48]1=[O:49].[Cl:1][c:2]1[cH:3][c:4]([NH:15][c:16]2[c:17]([C:29]#[N:30])[cH:18][n:19][c:20]3[cH:21][c:22]([F:28])[c:23]([O:26][CH3:27])[cH:24][c:25]23)[cH:5][cH:6][c:7]1[S:8][c:9]1[n:10]([CH3:14])[cH:11][cH:12][n:13]1.[N:31]1([CH:37]2[CH2:38][CH2:39][NH:40][CH2:41][CH2:42]2)[CH2:32][CH2:33][CH2:34][CH2:35][CH2:36]1>>[Cl:1][c:2]1[cH:3][c:4]([NH:15][c:16]2[c:17]([C:29]#[N:30])[cH:18][n:19][c:20]3[cH:21][c:22]([N:40]4[CH2:39][CH2:38][CH:37]([N:31]5[CH2:32][CH2:33][CH2:34][CH2:35][CH2:36]5)[CH2:42][CH2:41]4)[c:23]([O:26][CH3:27])[cH:24][c:25]23)[cH:5][cH:6][c:7]1[S:8][c:9]1[n:10]([CH3:14])[cH:11][cH:12][n:13]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-dfa6c84cebea4ab19d55360365dcbb57
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…