Hydrochloric Acid → 8-Chloro-7-methoxy-4-(3,4-dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline

HRID 2129526Notes

Reaction equation

HRID 2129526 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][c:10]2[c:11]([Cl:30])[c:12]([O:28][CH3:29])[cH:13][cH:14][c:15]2[CH:16]([c:18]2[cH:19][c:20]([O:26][CH3:27])[c:21]([O:24][CH3:25])[cH:22][cH:23]2)[CH2:17]1.[CH3:32][CH2:33][OH:34].[ClH:31]>>[NH:8]1[CH2:9][c:10]2[c:11]([Cl:30])[c:12]([O:28][CH3:29])[cH:13][cH:14][c:15]2[CH:16]([c:18]2[cH:19][c:20]([O:26][CH3:27])[c:21]([O:24][CH3:25])[cH:22][cH:23]2)[CH2:17]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 107884262-Benzyl-8-chloro-7-methoxy-4-(3,4-dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline

Product 1

HCID 106166778-Chloro-7-methoxy-4-(3,4-dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline

Sources & evidence

ORD record
ord-1784ac0760934ffe8c3a55f84c25c77a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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