Potassium Cation → tert-butyl 6-(2-(dimethylamino)ethoxy)-3,4-dihydro-1H-pyrido[4,3-b]indole-2(5H)-carboxylate

HRID 2129549Notes

Reaction equation

HRID 2129549 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[c:11]([nH:12][c:13]3[c:14]([I:19])[cH:15][cH:16][cH:17][c:18]23)[CH2:20][CH2:21]1.[CH3:30][N:31]([CH2:32][CH2:33][OH:34])[CH3:35].[Cl:36][CH2:37][Cl:38].[Cu:39][I:40].[K+:27].[K+:28].[K+:29].[P:22]([O-:23])([O-:24])([O-:25])=[O:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[c:11]([nH:12][c:13]3[c:14]([O:34][CH2:33][CH2:32][N:31]([CH3:30])[CH3:35])[cH:15][cH:16][cH:17][c:18]23)[CH2:20][CH2:21]1

Participants

7

Reactant 6

HCID 813Potassium Cation3×HCID 1061PhosphateHCID 6344DichloromethaneHCID 79022-(Dimethylamino)ethanolHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 21952696tert-Butyl-6-iodo-3,4-dihydro-1H-pyrido[4,3-b]indole-2(5H)-carboxylate

Product 1

HCID 57541297tert-butyl 6-(2-(dimethylamino)ethoxy)-3,4-dihydro-1H-pyrido[4,3-b]indole-2(5H)-carboxylate

Sources & evidence

ORD record
ord-90f74838948d49099839f31a81d8eab5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…