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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2129930Generated: October 31, 2026

Tetrahydrofuran → 3-Cyclopentyl-2-(4-trifluoromethyl-phenyl)-propionic acid

https://huagongshe.com/reaction/2129930

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantHexamethylphosphoramideHCID 12679—
ReactantLithium ionHCID 28486—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reactant(Iodomethyl)cyclopentaneHCID 2762531—
ReactantDiisopropylamideHCID 5062348—
Product3-Cyclopentyl-2-(4-trifluoromethyl-phenyl)-propionic acidHCID 22315279—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-95f002c575fa476db0d2cb8f95bf3601
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)