Tetrahydrofuran → 3-Cyclopentyl-2-(4-trifluoromethyl-phenyl)-propionic acid
Reaction equation
[CH3:30][N:31]([CH3:32])[P:33]([N:34]([CH3:35])[CH3:36])([N:37]([CH3:38])[CH3:39])=[O:40].[CH3:46][N:47]([P:48]([N:49]([CH3:50])[CH3:51])([N:52]([CH3:53])[CH3:54])=[O:55])[CH3:56].[CH:1]([N-:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[F:9][C:10]([c:11]1[cH:12][cH:13][c:14]([CH2:17][C:18](=[O:19])[OH:20])[cH:15][cH:16]1)([F:21])[F:22].[I:23][CH2:24][CH:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1.[Li+:8].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1>>[F:9][C:10]([c:11]1[cH:12][cH:13][c:14]([CH:17]([C:18](=[O:19])[OH:20])[CH2:24][CH:25]2[CH2:26][CH2:27][CH2:28][CH2:29]2)[cH:15][cH:16]1)([F:21])[F:22]Participants
7
Sources & evidence
- ORD record
- ord-95f002c575fa476db0d2cb8f95bf3601
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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