Hydrochloric Acid → (4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-[3-(3-amino-prop-1-ynyl)-phenyl]-methanone

HRID 2130136Notes

Reaction equation

HRID 2130136 reaction equation
[C:2]([O:3][C:4](=[O:5])[NH:8][CH2:9][C:10]#[C:11][c:12]1[cH:13][c:14]([C:18](=[O:19])[c:20]2[cH:21][n:22]([CH:30]3[CH2:31][CH2:32][CH2:33][CH2:34]3)[c:23]3[n:24][cH:25][n:26][c:27]([NH2:29])[c:28]23)[cH:15][cH:16][cH:17]1)([CH3:6])([CH3:7])[CH3:35].[CH3:36][OH:37].[ClH:1]>>[NH2:8][CH2:9][C:10]#[C:11][c:12]1[cH:13][c:14]([C:18](=[O:19])[c:20]2[cH:21][n:22]([CH:30]3[CH2:31][CH2:32][CH2:33][CH2:34]3)[c:23]3[n:24][cH:25][n:26][c:27]([NH2:29])[c:28]23)[cH:15][cH:16][cH:17]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 67219053{3-[3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-prop-2-ynyl}-carbamic acid tert-butyl ester

Product 1

HCID 67219393(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-[3-(3-amino-prop-1-ynyl)-phenyl]-methanone

Sources & evidence

ORD record
ord-7ee473fd7caf44ae9135083d6fdfc549
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…