Bicarbonate Ion → tert-butyl 3-[1H-benzimidazole-2-carbonyl(2-methylpropyl)amino]-5-(morpholine-4-carbonyl)piperidine-1-carboxylate
Reaction equation
[C:40]([OH:41])(=[O:42])[O-:43].[CH3:14][CH:15]([CH2:16][NH:17][CH:18]1[CH2:19][N:20]([C:32](=[O:33])[O:34][C:35]([CH3:36])([CH3:37])[CH3:38])[CH2:21][CH:22]([C:24](=[O:25])[N:26]2[CH2:27][CH2:28][O:29][CH2:30][CH2:31]2)[CH2:23]1)[CH3:39].[Cl:1][C:2]([c:3]1[n:4][c:5]2[c:6]([nH:7]1)[cH:8][cH:9][cH:10][cH:11]2)([Cl:12])[Cl:13].[Na+:44].[O:46]1[CH2:47][CH2:48][CH2:49][CH2:50]1.[OH2:45]>>[C:2]([c:3]1[nH:4][c:5]2[c:6]([n:7]1)[cH:8][cH:9][cH:10][cH:11]2)([N:17]([CH2:16][CH:15]([CH3:14])[CH3:39])[CH:18]1[CH2:19][N:20]([C:32](=[O:33])[O:34][C:35]([CH3:36])([CH3:37])[CH3:38])[CH2:21][CH:22]([C:24](=[O:25])[N:26]2[CH2:27][CH2:28][O:29][CH2:30][CH2:31]2)[CH2:23]1)=[O:41]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-6692e691068c4bd490070f97c3e1889f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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