Dimethyl Sulfoxide → Tert-butyl 4-(5-chloro-4-iodopyridin-2-yl-amino)piperidine-1-carboxylate

HRID 2130233Notes

Reaction equation

HRID 2130233 reaction equation
[CH3:24][S:25]([CH3:26])=[O:27].[CH3:28][CH2:29][O:30][C:31](=[O:32])[CH3:33].[Cl:1][c:2]1[c:3]([I:9])[cH:4][c:5]([F:8])[n:6][cH:7]1.[NH2:10][CH:11]1[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]1>>[Cl:1][c:2]1[c:3]([I:9])[cH:4][c:5]([NH:10][CH:11]2[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]2)[n:6][cH:7]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 8857Ethyl AcetateHCID 12682914-Amino-1-Boc-piperidineHCID 218653365-Chloro-2-fluoro-4-iodopyridine

Product 1

HCID 66936969Tert-butyl 4-(5-chloro-4-iodopyridin-2-yl-amino)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-592a976eeda84deba58486a8626b6e8b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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