Hydrochloric Acid → 2-[(4-{2-[(4'-Fluorobiphenyl-4-yl)oxy]-1-hydroxyethyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester
Reaction equation
[BH4-:34].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([C:7]([CH3:8])([CH3:9])[S:10][c:11]1[s:12][cH:13][c:14]([C:16]([CH2:17][O:18][c:19]2[cH:20][cH:21][c:22](-[c:25]3[cH:26][cH:27][c:28]([F:31])[cH:29][cH:30]3)[cH:23][cH:24]2)=[O:32])[n:15]1)=[O:33].[CH3:38][CH2:39][OH:40].[ClH:37].[Na+:35].[OH2:36]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([C:7]([CH3:8])([CH3:9])[S:10][c:11]1[s:12][cH:13][c:14]([CH:16]([CH2:17][O:18][c:19]2[cH:20][cH:21][c:22](-[c:25]3[cH:26][cH:27][c:28]([F:31])[cH:29][cH:30]3)[cH:23][cH:24]2)[OH:32])[n:15]1)=[O:33]Participants
7
Sources & evidence
- ORD record
- ord-f345eeda8ad442dab4779d653616b824
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…