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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2130507Generated: November 1, 2026

(6-(3-Methylisothiazol-5-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methanamine → 4-(8-((6-(3,5-Difluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methylamino)-1,5-naphthyridin-3-yl)piperidin-4-ol

https://huagongshe.com/reaction/2130507

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(6-(3-Methylisothiazol-5-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methanamineHCID 57691076—
ReactantTert-butyl 4-(8-((6-(3,5-difluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methylamino)-1,5-naphthyridin-3-yl)-4-hydroxypiperidine-1-carboxylateHCID 57691230—
Product4-(8-((6-(3,5-Difluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methylamino)-1,5-naphthyridin-3-yl)piperidin-4-olHCID 44180598—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-299f8746a49e4b9098d8e295b6bda4d2
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)