Tetrahydrofuran → Spiro[indole-3,4'-oxan]-2(1H)-one
Reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:16][N:17]([CH3:18])[CH2:19][CH2:20][N:21]([CH3:22])[CH3:23].[I:24][CH2:25][CH2:26][O:27][CH2:28][CH2:29][I:30].[Li:1][CH2:2][CH2:3][CH2:4][CH3:5].[NH:6]1[C:7](=[O:15])[CH2:8][c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]21>>[NH:6]1[C:7](=[O:15])[C:8]2([c:9]3[cH:10][cH:11][cH:12][cH:13][c:14]31)[CH2:25][CH2:26][O:27][CH2:28][CH2:29]2Participants
6
Sources & evidence
- ORD record
- ord-87389da789bc456592e3b230fd96f663
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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