Methane → t-Butyl 4-[4-(4-amino-2-fluorophenoxy)pyridin-2-ylcarbamoyl]piperidine-1-carboxylate
Reaction equation
[C:36].[CH3:34][OH:35].[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][c:7]([NH:11][C:12](=[O:13])[CH:14]3[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]3)[n:8][cH:9][cH:10]2)[cH:27][cH:28][c:29]([N+:31]([O-:32])=[O:33])[cH:30]1.[Pd:37]>>[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][c:7]([NH:11][C:12](=[O:13])[CH:14]3[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]3)[n:8][cH:9][cH:10]2)[cH:27][cH:28][c:29]([NH2:31])[cH:30]1Participants
5
Sources & evidence
- ORD record
- ord-d60cc634ded34ae18657a79094b6b995
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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