Hydrochloric Acid → 4-[4-(6-Chloro-2-naphthoyl)-1-piperidyl]-1-(4-fluorophenyl)-1-butanone
Reaction equation
[C:34](=[O:35])([OH:36])[O-:37].[CH3:41][c:42]1[cH:43][cH:44][cH:45][cH:46][cH:47]1.[Cl:21][CH2:22][CH2:23][CH2:24][C:25](=[O:26])[c:27]1[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]1.[ClH:1].[I-:40].[K+:38].[K+:39].[NH:2]1[CH2:3][CH2:4][CH:5]([C:8](=[O:9])[c:10]2[cH:11][c:12]3[cH:13][cH:14][c:15]([Cl:20])[cH:16][c:17]3[cH:18][cH:19]2)[CH2:6][CH2:7]1>>[N:2]1([CH2:22][CH2:23][CH2:24][C:25](=[O:26])[c:27]2[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]2)[CH2:3][CH2:4][CH:5]([C:8](=[O:9])[c:10]2[cH:11][c:12]3[cH:13][cH:14][c:15]([Cl:20])[cH:16][c:17]3[cH:18][cH:19]2)[CH2:6][CH2:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-f019632460be4ab59846a8ff38069f63
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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