Acetone → 2-chloro-4-(3-chlorophenyl)-alpha-(1-methyl-1H-imidazol-5-yl)-alpha-(4-methylphenyl)-6-quinazolinemethanol
Reaction equation
[CH2:47]1[O:48][CH2:49][CH2:50][CH2:51]1.[CH3:1][n:2]1[cH:3][cH:4][n:5][cH:6]1.[CH3:52][C:53](=[O:54])[CH3:55].[CH3:7][CH2:8][CH2:9][CH2:10][Li:11].[Cl:12][Si:13]([CH2:14][CH3:15])([CH2:16][CH3:17])[CH2:18][CH3:19].[Cl:20][c:21]1[n:22][c:23]2[cH:24][cH:25][c:26]([C:38](=[O:39])[c:40]3[cH:41][cH:42][c:43]([CH3:46])[cH:44][cH:45]3)[cH:27][c:28]2[c:29](-[c:31]2[cH:32][c:33]([Cl:37])[cH:34][cH:35][cH:36]2)[n:30]1.[OH2:56]>>[CH3:1][n:2]1[c:3]([C:38]([c:26]2[cH:25][cH:24][c:23]3[n:22][c:21]([Cl:20])[n:30][c:29](-[c:31]4[cH:32][c:33]([Cl:37])[cH:34][cH:35][cH:36]4)[c:28]3[cH:27]2)([OH:39])[c:40]2[cH:41][cH:42][c:43]([CH3:46])[cH:44][cH:45]2)[cH:4][n:5][cH:6]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-04bac59576a1407282b6beb6e2d7533a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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