Acetonitrile → 4-(1-Benzyloxycarbonylpiperidine-2-carbonyl)piperazine-1-carboxylic acid tert-butyl ester

HRID 2131246Notes

Reaction equation

HRID 2131246 reaction equation
[C:1](=[O:2])([O:3][CH2:4][c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1)[N:11]1[CH:12]([C:17](=[O:18])[OH:19])[CH2:13][CH2:14][CH2:15][CH2:16]1.[C:27](=[O:28])([O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[N:34]1[CH2:35][CH2:36][NH:37][CH2:38][CH2:39]1.[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[CH3:40][C:41]#[N:42]>>[C:1](=[O:2])([O:3][CH2:4][c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1)[N:11]1[CH:12]([C:17](=[O:19])[N:37]2[CH2:36][CH2:35][N:34]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:39][CH2:38]2)[CH2:13][CH2:14][CH2:15][CH2:16]1

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 8471TriethylamineHCID 143452tert-Butyl piperazine-1-carboxylateHCID 44310261-Carbobenzoxy-2-piperidinecarboxylic Acid

Product 1

HCID 684578424-(1-Benzyloxycarbonylpiperidine-2-carbonyl)piperazine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-e3fe9402f8ed4ab588e9858deb6b0bfd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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