Hydrochloric Acid → Racemic (4aSR,7aSR)-7a-(5-Bromo-2-fluorophenyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-2-amine

HRID 2131409Notes

Reaction equation

HRID 2131409 reaction equation
[Br:2][c:3]1[cH:4][cH:5][c:6]([F:27])[c:7]([C:9]23[N:10]=[C:11]([NH:18][C:19](=[O:20])[c:21]4[cH:22][cH:23][cH:24][cH:25][cH:26]4)[S:12][CH2:13][CH:14]2[CH2:15][O:16][CH2:17]3)[cH:8]1.[ClH:1]>>[Br:2][c:3]1[cH:4][cH:5][c:6]([F:27])[c:7]([C:9]23[N:10]=[C:11]([NH2:18])[S:12][CH2:13][CH:14]2[CH2:15][O:16][CH2:17]3)[cH:8]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 57504886N-(7a-(5-bromo-2-fluorophenyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-2-yl)benzamide

Product 1

HCID 66847566Racemic (4aSR,7aSR)-7a-(5-Bromo-2-fluorophenyl)-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-2-amine

Sources & evidence

ORD record
ord-9da4a6cc75364b1db08a382fd98247a5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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