Water → 1-Methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine

HRID 2131420Notes

Reaction equation

HRID 2131420 reaction equation
[Br:26][c:27]1[cH:28][cH:29][c:30]([CH:33]2[CH2:34][CH2:35][N:36]([CH3:39])[CH2:37][CH2:38]2)[cH:31][cH:32]1.[C:1]([O:2][CH:3]1[CH2:4][CH2:5][N:6]([c:11]2[cH:12][cH:13][c:14]([B:17]3[O:18][C:19]([CH3:24])([CH3:25])[C:20]([CH3:22])([CH3:23])[O:21]3)[cH:15][cH:16]2)[CH2:7][CH2:8]1)(=[O:9])[CH3:10].[CH3:40][CH2:41][O:42][C:43]([CH3:44])=[O:45].[OH2:46]>>[c:11]1([CH:33]2[CH2:34][CH2:35][N:36]([CH3:39])[CH2:37][CH2:38]2)[cH:12][cH:13][c:14]([B:17]2[O:18][C:19]([CH3:24])([CH3:25])[C:20]([CH3:22])([CH3:23])[O:21]2)[cH:15][cH:16]1

Participants

5

Reactant 4

HCID 962WaterHCID 8857Ethyl AcetateHCID 213638774-(4-Bromophenyl)-1-methylpiperidineHCID 667303481-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidin-4-yl acetate

Product 1

HCID 584862351-Methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine

Sources & evidence

ORD record
ord-e2003b97ceaa4ed5ae054283ef76392b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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