Bicarbonate Ion → Methyl 1-(4-(6-bromo-3-nitroquinolin-4-ylamino)-2-(trifluoromethyl)phenyl)piperidine-4-carboxylate
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([Cl:15])[c:6]([N+:12](=[O:13])[O-:14])[cH:7][n:8][c:9]2[cH:10][cH:11]1.[CH3:48][CH2:49][O:50][C:51]([CH3:52])=[O:53].[NH2:16][c:17]1[cH:18][c:19]([C:33]([F:34])([F:35])[F:36])[c:20]([N:23]2[CH2:24][CH2:25][CH:26]([C:29](=[O:30])[O:31][CH3:32])[CH2:27][CH2:28]2)[cH:21][cH:22]1.[Na+:41].[O-:37][C:38]([OH:39])=[O:40].[O:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([NH:16][c:17]3[cH:18][c:19]([C:33]([F:34])([F:35])[F:36])[c:20]([N:23]4[CH2:24][CH2:25][CH:26]([C:29](=[O:30])[O:31][CH3:32])[CH2:27][CH2:28]4)[cH:21][cH:22]3)[c:6]([N+:12](=[O:13])[O-:14])[cH:7][n:8][c:9]2[cH:10][cH:11]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-c6adba48a04547dda688b6754e8a2c62
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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