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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2131632Generated: November 2, 2026

Tetrahydrofuran → 1,1-Dimethylethyl 4-(3-cyanophenyl)-4-hydroxy-1-piperidinecarboxylate

https://huagongshe.com/reaction/2131632

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant3-BromobenzonitrileHCID 23381—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
ReactantButyllithiumHCID 178418339—
Product1,1-Dimethylethyl 4-(3-cyanophenyl)-4-hydroxy-1-piperidinecarboxylateHCID 22266166—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-bac8108489544a408b29d019cc86197e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)