Dichloromethane → 2-Chloro-trifluoromethyl-pyrimidine-5-carboxylic acid cyclohexylmethyl-amide

HRID 2131868Notes

Reaction equation

HRID 2131868 reaction equation
[CH3:23][CH2:24][N:25]([CH2:26][CH3:27])[CH2:28][CH3:29].[CH:15]1([CH2:21][NH2:22])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([C:12](=[O:13])[Cl:14])[c:6]([C:8]([F:9])([F:10])[F:11])[n:7]1.[Cl:30][CH2:31][Cl:32]>>[Cl:1][c:2]1[n:3][cH:4][c:5]([C:12](=[O:13])[NH:22][CH2:21][CH:15]2[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]2)[c:6]([C:8]([F:9])([F:10])[F:11])[n:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 76688CyclohexanemethylamineHCID 27367082-Chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl chloride

Product 1

HCID 579825812-Chloro-trifluoromethyl-pyrimidine-5-carboxylic acid cyclohexylmethyl-amide

Sources & evidence

ORD record
ord-cc768ad63cee4b2aa0e4508c3e1f9cfb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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