Benzo(B)Thiophene → Benzo[b]thiophen-2-yl(5-bromo-2-fluorophenyl)methanol
Reaction equation
[Br:15][c:16]1[cH:17][cH:18][c:19]([F:24])[c:20]([CH:21]=[O:22])[cH:23]1.[CH2:10]([Li:11])[CH2:12][CH2:13][CH3:14].[CH3:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1.[s:1]1[c:2]2[c:3]([cH:4][cH:5]1)[cH:6][cH:7][cH:8][cH:9]2>>[s:1]1[c:2]2[c:3]([cH:4][c:5]1[CH:21]([c:20]1[c:19]([F:24])[cH:18][cH:17][c:16]([Br:15])[cH:23]1)[OH:22])[cH:6][cH:7][cH:8][cH:9]2Participants
6
Sources & evidence
- ORD record
- ord-18e53296a63847a282367a1ad2088a4d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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