Hydrochloric Acid → N-(5-bromo-2-chloropyridin-3-yl)-4-fluorobenzenesulfonamide

HRID 2132251Notes

Reaction equation

HRID 2132251 reaction equation
[C:27](=[O:28])([O-:29])[O-:30].[CH2:35]1[O:36][CH2:37][CH2:38][O:39][CH2:40]1.[CH3:41][OH:42].[ClH:33].[F:16][c:17]1[cH:18][cH:19][c:20]([S:23](=[O:24])(=[O:25])[Cl:26])[cH:21][cH:22]1.[K+:31].[K+:32].[NH2:1][c:2]1[c:3]([Cl:9])[n:4][cH:5][c:6]([Br:8])[cH:7]1.[OH2:34].[cH:10]1[cH:11][cH:12][n:13][cH:14][cH:15]1>>[NH:1]([c:2]1[c:3]([Cl:9])[n:4][cH:5][c:6]([Br:8])[cH:7]1)[S:23]([c:20]1[cH:19][cH:18][c:17]([F:16])[cH:22][cH:21]1)(=[O:24])=[O:25]

Participants

10

Reactant 9

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 887MethanolHCID 962WaterHCID 1049PyridineHCID 95884-Fluorobenzenesulfonyl chlorideHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 218583543-Amino-5-bromo-2-chloropyridine

Product 1

HCID 53363354N-(5-bromo-2-chloropyridin-3-yl)-4-fluorobenzenesulfonamide

Sources & evidence

ORD record
ord-4f82a8377828490595f15d58b76f7f96
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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