N-methyl-2-pyrrolidone → HCID 67441006, compound

HRID 2132260Notes

Reaction equation

HRID 2132260 reaction equation
[CH3:32][N:33]1[CH2:34][CH2:35][CH2:36][C:37]1=[O:38].[Cl:1][c:2]1[cH:3][c:4]([CH:14]2[NH:15][c:16]3[cH:17][cH:18][c:19]([C:26](=[O:27])[OH:28])[cH:20][c:21]3[CH2:22][C:23]2([CH3:24])[CH3:25])[cH:5][c:6]([N:8]2[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[cH:7]1.[Na:29][C:30]#[N:31].[Ni:39]([Br:40])[Br:41]>>[c:2]1([C:30]#[N:31])[cH:3][c:4]([CH:14]2[NH:15][c:16]3[cH:17][cH:18][c:19]([C:26](=[O:27])[OH:28])[cH:20][c:21]3[CH2:22][C:23]2([CH3:24])[CH3:25])[cH:5][c:6]([N:8]2[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[cH:7]1

Participants

5

Reactant 4

HCID 13387N-methyl-2-pyrrolidoneHCID 278492Nickel(II) bromideHCID 534927082-(3-Chloro-5-morpholin-4-yl-phenyl)-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acidHCID 178511850HCID 178511850, compound

Product 1

HCID 67441006HCID 67441006, compound

Sources & evidence

ORD record
ord-27e503d06d5f48d0ac8025c2f0582099
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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