Methyl iodide → 5-Bromo-1-methylpyridin-2(1H)-one

HRID 2132267Notes

Reaction equation

HRID 2132267 reaction equation
[Br:1][c:2]1[cH:3][nH:4][c:5](=[O:8])[cH:6][cH:7]1.[C:9](=[O:10])([O-:11])[O-:12].[CH3:15][I:16].[CH3:17][C:18]([O:19][I:20]1([O:30][C:31]([CH3:32])=[O:33])([O:34][C:35]([CH3:36])=[O:37])[c:21]2[c:22]([cH:23][cH:24][cH:25][cH:26]2)[C:27](=[O:28])[O:29]1)=[O:38].[CH3:39][CH2:40][O:41][C:42](=[O:43])[CH3:44].[Cs+:13].[Cs+:14]>>[Br:1][c:2]1[cH:3][n:4]([CH3:9])[c:5](=[O:8])[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 6328Methyl iodideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 159087TriacetoxyperiodinaneHCID 5995285-Bromo-2-hydroxypyridine

Product 1

HCID 130240275-Bromo-1-methylpyridin-2(1H)-one

Sources & evidence

ORD record
ord-d69a3dcabb6a496cbc25f1335055b9f1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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