1,2-Dichloroethane → ethyl 4-[(2-chloro-4,4-difluoro-spiro[5H-thieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)methyl]-1-(3-fluoro-2-pyridyl)pyrazole-3-carboxylate
Reaction equation
[C:37]([O:38][BH-:39]([O:40][C:41](=[O:42])[CH3:43])[O:44][C:45](=[O:46])[CH3:47])(=[O:48])[CH3:49].[C:51](=[O:52])([OH:53])[O-:54].[Cl:20][c:21]1[cH:22][c:23]2[c:24]([s:36]1)[C:25]1([O:26][CH2:27][C:28]2([F:29])[F:30])[CH2:31][CH2:32][NH:33][CH2:34][CH2:35]1.[Cl:56][CH2:57][CH2:58][Cl:59].[F:1][c:2]1[c:3](-[n:8]2[n:9][c:10]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[c:11]([CH:13]=[O:14])[cH:12]2)[n:4][cH:5][cH:6][cH:7]1.[Na+:50].[Na+:55]>>[F:1][c:2]1[c:3](-[n:8]2[n:9][c:10]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[c:11]([CH2:13][N:33]3[CH2:32][CH2:31][C:25]4([c:24]5[c:23]([cH:22][c:21]([Cl:20])[s:36]5)[C:28]([F:29])([F:30])[CH2:27][O:26]4)[CH2:35][CH2:34]3)[cH:12]2)[n:4][cH:5][cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-9adc4ba6cae9438eb8d19e462b9a848d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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