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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2132501Generated: November 1, 2026

Water → 6-(8-Hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)nicotinonitrile

https://huagongshe.com/reaction/2132501

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantHexaneHCID 8058—
Reactant1,4-Dioxaspiro[4.5]decan-8-oneHCID 567415—
Reactant6-Bromopyridine-3-carbonitrileHCID 5005718—
ReactantButyllithiumHCID 178418339—
Product6-(8-Hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)nicotinonitrileHCID 66787727—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-826af6a36ea24b97af25162052fc0eb1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)