Acetate → 3-(4-(Benzyloxy)phenyl)pyridine

HRID 213251Notes

Reaction equation

HRID 213251 reaction equation
[C:25](=[O:26])([O-:27])[O-:28].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([B:15]([OH:16])[OH:17])[cH:13][cH:14]1.[CH3:50][O:51][CH2:52][CH2:53][O:54][CH3:55].[CH3:66][CH2:67][OH:68].[I:18][c:19]1[cH:20][n:21][cH:22][cH:23][cH:24]1.[K+:29].[K+:30].[O-:57][C:58]([CH3:59])=[O:60].[O-:61][C:62]([CH3:63])=[O:64].[OH2:65].[Pd+2:56].[c:31]1([P:32]([c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[cH:45][cH:46][cH:47][cH:48][cH:49]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12](-[c:19]2[cH:20][n:21][cH:22][cH:23][cH:24]2)[cH:13][cH:14]1

Participants

11

Reactant 10

HCID 175Acetate2×HCID 702EthanolHCID 813Potassium Cation2×HCID 962WaterHCID 80711,2-DimethoxyethaneHCID 11776TriphenylphosphineHCID 19660Carbonate IonHCID 707143-IodopyridineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 27343144-Benzyloxy-phenylboronic acid

Product 1

HCID 672269493-(4-(Benzyloxy)phenyl)pyridine

Sources & evidence

ORD record
ord-81886ea0877d470e9e1f89a24022ff69
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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