Dichloromethane → Dimethyl 2-(2,5-difluorobenzyl)piperidine-1,4-dicarboxylate

HRID 2132571Notes

Reaction equation

HRID 2132571 reaction equation
[C:29]([O:30][CH3:31])(=[O:32])[Cl:33].[CH:20]([N:21]([CH2:22][CH3:23])[CH:24]([CH3:25])[CH3:26])([CH3:27])[CH3:28].[Cl:34][CH2:35][Cl:36].[F:1][c:2]1[c:3]([CH2:4][CH:5]2[NH:6][CH2:7][CH2:8][CH:9]([C:11](=[O:12])[O:13][CH3:14])[CH2:10]2)[cH:15][c:16]([F:19])[cH:17][cH:18]1>>[F:1][c:2]1[c:3]([CH2:4][CH:5]2[N:6]([C:29]([O:30][CH3:31])=[O:32])[CH2:7][CH2:8][CH:9]([C:11](=[O:12])[O:13][CH3:14])[CH2:10]2)[cH:15][c:16]([F:19])[cH:17][cH:18]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6586Methyl chloroformateHCID 81531DiisopropylethylamineHCID 66731652HCID 66731652, compound

Product 1

HCID 66734456Dimethyl 2-(2,5-difluorobenzyl)piperidine-1,4-dicarboxylate

Sources & evidence

ORD record
ord-d01673e2dc5943d4a0c4ded4e4417fe4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…