Ethyl Acetate → benzyl N-(4-chloro-3-hydroxy-1-naphthalen-1-ylbutan-2-yl)carbamate

HRID 2133324Notes

Reaction equation

HRID 2133324 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH:12]([C:13]([CH2:14][Cl:15])=[O:16])[CH2:17][c:18]1[cH:19][cH:20][cH:21][c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]12.[CH3:28][CH2:29][O:30][C:31](=[O:32])[CH3:33].[Cl:60][Rh+:61][C:62]1=[C:70]([CH3:71])[C:68]([CH3:69])=[C:66]([CH3:67])[C:63]1([CH3:64])[CH3:65].[c:34]1([CH3:35])[cH:36][cH:37][c:38]([S:39]([NH:40][CH:41]([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[CH:48]([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[NH2:55])(=[O:56])=[O:57])[cH:58][cH:59]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH:12]([CH:13]([CH2:14][Cl:15])[OH:16])[CH2:17][c:18]1[cH:19][cH:20][cH:21][c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]12

Participants

5

Reactant 4

HCID 8857Ethyl AcetateHCID 3608242N-(2-amino-1,2-diphenylethyl)-4-methylbenzenesulfonamideHCID 178425026HCID 178425026, compoundHCID 178523123benzyl N-(4-chloro-1-naphthalen-1-yl-3-oxobutan-2-yl)carbamate

Product 1

HCID 178523124benzyl N-(4-chloro-3-hydroxy-1-naphthalen-1-ylbutan-2-yl)carbamate

Sources & evidence

ORD record
ord-cd8bc7356ba44fa9b42985b1dc6e82ba
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…