Tetrahydrofuran → Imidazo[1,5-a]pyrazine-1,7(8h)-dicarboxylic acid,3-benzoyl-5,6-dihydro-,7-(1,1-dimethylethyl)ester

HRID 2133490Notes

Reaction equation

HRID 2133490 reaction equation
[Br:1][c:2]1[n:3][c:4]([C:18](=[O:19])[OH:20])[c:5]2[n:6]1[CH2:7][CH2:8][N:9]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[CH2:10]2.[C:33]([Li:34])([CH3:35])([CH3:36])[CH3:37].[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[CH3:21][O:22][N:23]([CH3:24])[C:25](=[O:26])[c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[c:2]1([C:25](=[O:26])[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[n:3][c:4]([C:18](=[O:19])[OH:20])[c:5]2[n:6]1[CH2:7][CH2:8][N:9]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[CH2:10]2

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 569575N-Methoxy-N-methylbenzamideHCID 576354283-bromo-7-[(tert-butoxy)carbonyl]-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1-carboxylic acidHCID 178418306HCID 178418306, compound

Product 1

HCID 57635676Imidazo[1,5-a]pyrazine-1,7(8h)-dicarboxylic acid,3-benzoyl-5,6-dihydro-,7-(1,1-dimethylethyl)ester

Sources & evidence

ORD record
ord-a806007a6d7e462db80bfe83edc3b79d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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