Hydrochloric Acid → N2-(4-(2-Methyl-1H-imidazol-1-yl)phenyl)-N4-((tetrahydro-2H-pyran-4-yl)methyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2,4-diamine

HRID 2133686Notes

Reaction equation

HRID 2133686 reaction equation
[CH3:1][c:2]1[n:3](-[c:7]2[cH:8][cH:9][c:10]([NH:13][c:14]3[n:15][c:16]([NH:31][CH2:32][CH:33]4[CH2:34][CH2:35][O:36][CH2:37][CH2:38]4)[c:17]4[c:18]([n:19]3)[CH2:20][CH2:21][N:22]([C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[CH2:23]4)[cH:11][cH:12]2)[cH:4][cH:5][n:6]1.[CH3:40][OH:41].[ClH:39]>>[CH3:1][c:2]1[n:3](-[c:7]2[cH:8][cH:9][c:10]([NH:13][c:14]3[n:15][c:16]([NH:31][CH2:32][CH:33]4[CH2:34][CH2:35][O:36][CH2:37][CH2:38]4)[c:17]4[c:18]([n:19]3)[CH2:20][CH2:21][NH:22][CH2:23]4)[cH:11][cH:12]2)[cH:4][cH:5][n:6]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 59333695tert-Butyl 2-(4-(2-methyl-1H-imidazol-1-yl)phenylamino)-4-((tetrahydro-2H-pyran-4-yl)methylamino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate

Product 1

HCID 59333815N2-(4-(2-Methyl-1H-imidazol-1-yl)phenyl)-N4-((tetrahydro-2H-pyran-4-yl)methyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2,4-diamine

Sources & evidence

ORD record
ord-547f9f8e46f146d7aac58deb2da79c9a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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