Hydrogen Bromide → 6-Methoxy-2'-oxo-1'-(pyridin-2-ylmethyl)-1',2'-dihydrospiro[1-benzofuran-3,3'-indole]-5-carbonitrile
Reaction equation
[Br:10][CH2:11][c:12]1[o:13][c:14]([C:15]([F:16])([F:17])[F:18])[cH:19][cH:20]1.[Br:2][CH2:3][c:4]1[n:5][cH:6][cH:7][cH:8][cH:9]1.[BrH:1].[CH3:21][O:22][c:23]1[cH:24][c:25]2[c:26]([cH:39][c:40]1[C:41]#[N:42])[C:27]1([CH2:28][O:29]2)[C:30](=[O:38])[NH:31][c:32]2[cH:33][cH:34][cH:35][cH:36][c:37]21.[CH3:43][c:44]1[c:45]2[cH:46][c:47]3[c:60]([cH:61][c:62]2[o:63][n:64]1)[O:59][CH2:58][C:48]31[c:49]2[c:50]([cH:51][cH:52][cH:53][cH:54]2)[NH:55][C:56]1=[O:57]>>[CH2:3]([c:4]1[n:5][cH:6][cH:7][cH:8][cH:9]1)[N:31]1[C:30](=[O:38])[C:27]2([c:26]3[c:25]([cH:24][c:23]([O:22][CH3:21])[c:40]([C:41]#[N:42])[cH:39]3)[O:29][CH2:28]2)[c:37]2[c:32]1[cH:33][cH:34][cH:35][cH:36]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-22c6ae9d286b49979391f6617f096d3d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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