Formic Acid → N-(6-chloro-7-fluoro-9H-beta-carbolin-8-yl)-2-methyl-nicotinamide
Reaction equation
[CH3:17][c:18]1[c:19]([C:20](=[O:21])[OH:22])[cH:23][cH:24][cH:25][n:26]1.[CH3:27][CH2:28][N:29]=[C:30]=[N:31][CH2:32][CH2:33][CH2:34][N:35]([CH3:36])[CH3:37].[CH:38]([OH:39])=[O:40].[Cl:1][c:2]1[cH:3][c:4]2[c:5]3[cH:6][cH:7][n:8][cH:9][c:10]3[nH:11][c:12]2[c:13]([NH2:16])[c:14]1[F:15].[cH:41]1[cH:42][cH:43][n:44][cH:45][cH:46]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]3[cH:6][cH:7][n:8][cH:9][c:10]3[nH:11][c:12]2[c:13]([NH:16][C:20]([c:19]2[c:18]([CH3:17])[n:26][cH:25][cH:24][cH:23]2)=[O:21])[c:14]1[F:15]Participants
6
Sources & evidence
- ORD record
- ord-e0a306c0c87d490c936f86509fc5b55c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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