Dimethylformamide → (2-Chloro-5-methyl-pyrimidin-4-yl)-(4-chloro-3-trifluoromethyl-phenyl)-amine
Reaction equation
[Br:10][c:11]1[cH:12][c:13]([C:18]([F:19])([F:20])[F:21])[c:14]([Cl:17])[cH:15][cH:16]1.[C:22](=[O:23])([O-:24])[O-:25].[Cl:1][c:2]1[n:3][cH:4][c:5]([CH3:9])[c:6]([NH2:8])[n:7]1.[Cs+:26].[Cs+:27].[O:28]1[CH2:29][CH2:30][O:31][CH2:32][CH2:33]1.[O:34]=[CH:35][N:36]([CH3:37])[CH3:38].[O:41]=[C:42]([CH:43]=[CH:44][c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1)[CH:51]=[CH:52][c:53]1[cH:54][cH:55][cH:56][cH:57][cH:58]1.[O:59]=[C:60]([CH:61]=[CH:62][c:63]1[cH:64][cH:65][cH:66][cH:67][cH:68]1)[CH:69]=[CH:70][c:71]1[cH:72][cH:73][cH:74][cH:75][cH:76]1.[O:77]=[C:78]([CH:79]=[CH:80][c:81]1[cH:82][cH:83][cH:84][cH:85][cH:86]1)[CH:87]=[CH:88][c:89]1[cH:90][cH:91][cH:92][cH:93][cH:94]1.[Pd:39].[Pd:40]>>[Cl:1][c:2]1[n:3][cH:4][c:5]([CH3:9])[c:6]([NH:8][c:11]2[cH:12][c:13]([C:18]([F:19])([F:20])[F:21])[c:14]([Cl:17])[cH:15][cH:16]2)[n:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-da678fa900fa4e10b5d52f4e60d9499d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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