Methylamine → 4-Chloro-N-cyclopropyl-3-[3-[(1-methyl-1-{2-[2-(methylamino)ethoxy]phenyl}ethyl)amino]-2-oxopyrazin-1(2H)-yl]benzamide

HRID 2134550Notes

Reaction equation

HRID 2134550 reaction equation
[CH3:35][NH2:36].[CH3:37][C:38]#[N:39].[Cl:1][c:2]1[c:3](-[n:14]2[c:15](=[O:34])[c:16]([NH:20][C:21]([CH3:22])([CH3:23])[c:24]3[c:25]([O:30][CH2:31][CH2:32][Cl:33])[cH:26][cH:27][cH:28][cH:29]3)[n:17][cH:18][cH:19]2)[cH:4][c:5]([C:6](=[O:7])[NH:8][CH:9]2[CH2:10][CH2:11]2)[cH:12][cH:13]1>>[Cl:1][c:2]1[c:3](-[n:14]2[c:15](=[O:34])[c:16]([NH:20][C:21]([CH3:22])([CH3:23])[c:24]3[c:25]([O:30][CH2:31][CH2:32][NH:36][CH3:35])[cH:26][cH:27][cH:28][cH:29]3)[n:17][cH:18][cH:19]2)[cH:4][c:5]([C:6](=[O:7])[NH:8][CH:9]2[CH2:10][CH2:11]2)[cH:12][cH:13]1

Participants

4

Reactant 3

HCID 6329MethylamineHCID 6342AcetonitrileHCID 666900194-Chloro-3-[3-({1-[2-(2-chloroethoxy)phenyl]-1-methylethyl}amino)-2-oxopyrazin-1(2H)-yl]-N-cyclopropylbenzamide

Product 1

HCID 666896934-Chloro-N-cyclopropyl-3-[3-[(1-methyl-1-{2-[2-(methylamino)ethoxy]phenyl}ethyl)amino]-2-oxopyrazin-1(2H)-yl]benzamide

Sources & evidence

ORD record
ord-cae72debf7b74771a28194314aaf0865
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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