Potassium Cation → 1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-phenyl-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[C:10]2([CH2:14][OH:15])[CH2:11][CH:12]2[CH2:13]1.[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[CH3:22][Si:23]([N-:24][Si:25]([CH3:26])([CH3:27])[CH3:28])([CH3:29])[CH3:30].[I:32][CH2:33][c:34]1[cH:35][c:36]([C:44]([F:45])([F:46])[F:47])[cH:37][c:38]([C:40]([F:41])([F:42])[F:43])[cH:39]1.[K+:31].[OH2:48]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[C:10]2([CH2:14][O:15][CH2:33][c:34]3[cH:35][c:36]([C:44]([F:45])([F:46])[F:47])[cH:37][c:38]([C:40]([F:41])([F:42])[F:43])[cH:39]3)[CH2:11][CH:12]2[CH2:13]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-341e1d1f6d114e8baef0023d56313ab6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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