Dichloromethane → 3-bromo-7-(2-chloro-4,6-dimethylphenyl)-2-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-b]pyridine

HRID 2134987Notes

Reaction equation

HRID 2134987 reaction equation
[Cl:1][c:2]1[c:3]([N:10]2[c:11]3[c:12]([c:16](=[O:20])[n:17]([CH3:19])[nH:18]3)[CH2:13][CH2:14][CH2:15]2)[c:4]([CH3:9])[cH:5][c:6]([CH3:8])[cH:7]1.[Cl:26][CH2:27][Cl:28].[P:21]([Br:22])([Br:23])([Br:24])=[O:25]>>[Cl:1][c:2]1[c:3]([N:10]2[c:11]3[c:12]([c:16]([Br:23])[n:17]([CH3:19])[n:18]3)[CH2:13][CH2:14][CH2:15]2)[c:4]([CH3:9])[cH:5][c:6]([CH3:8])[cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24613Phosphorus oxybromideHCID 12143941HCID 12143941, compound

Product 1

HCID 113602163-bromo-7-(2-chloro-4,6-dimethylphenyl)-2-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-b]pyridine

Sources & evidence

ORD record
ord-2bc3076f94034536aa94911c9a9ba1fe
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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