Dimethyl Sulfoxide → 5-chloro-N-((1-(4-(3-(2-hydroxyethoxy)-2-oxopyridin-1(2H)-yl)phenyl)-1H-imidazol-4-yl)methyl)thiophene-2-carboxamide

HRID 2134989Notes

Reaction equation

HRID 2134989 reaction equation
[Br:30][CH2:31][CH2:32][OH:33].[C:34](=[O:35])([O-:36])[O-:37].[CH3:40][S:41]([CH3:42])=[O:43].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7](=[O:8])[NH:9][CH2:10][c:11]2[n:12][cH:13][n:14](-[c:16]3[cH:17][cH:18][c:19](-[n:22]4[c:23](=[O:29])[c:24]([OH:28])[cH:25][cH:26][cH:27]4)[cH:20][cH:21]3)[cH:15]2)[s:6]1.[Cs+:38].[Cs+:39]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7](=[O:8])[NH:9][CH2:10][c:11]2[n:12][cH:13][n:14](-[c:16]3[cH:17][cH:18][c:19](-[n:22]4[c:23](=[O:29])[c:24]([O:28][CH2:31][CH2:32][OH:33])[cH:25][cH:26][cH:27]4)[cH:20][cH:21]3)[cH:15]2)[s:6]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 108982-BromoethanolHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 24760094HCID 24760094, compound

Product 1

HCID 247602305-chloro-N-((1-(4-(3-(2-hydroxyethoxy)-2-oxopyridin-1(2H)-yl)phenyl)-1H-imidazol-4-yl)methyl)thiophene-2-carboxamide

Sources & evidence

ORD record
ord-c370e353bd204f37a7211bc91072276d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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