Acetic Acid → 1-[2-(4-chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]-1-ethanone

HRID 2135182Notes

Reaction equation

HRID 2135182 reaction equation
[CH3:29][Li:30].[CH3:31][C:32](=[O:33])[OH:34].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9](-[c:19]3[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[CH3:28])[cH:23][cH:24]3)[cH:10][c:11]([C:13](=[O:14])[N:15]([O:16][CH3:17])[CH3:18])[n:12]2)[cH:6][cH:7]1.[O:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9](-[c:19]3[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[CH3:28])[cH:23][cH:24]3)[cH:10][c:11]([C:13](=[O:14])[CH3:31])[n:12]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 8028TetrahydrofuranHCID 229982182-(4-chlorophenyl)-N-methoxy-N-methyl-1-[4-(methylsulfonyl)phenyl]-1H-imidazole-4-carboxamideHCID 178418348HCID 178418348, compound

Product 1

HCID 229977331-[2-(4-chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]-1-ethanone

Sources & evidence

ORD record
ord-c89122ddca304e448d14137fb011f258
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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