O-Xylene → N-(6-chloro-pyrazin-2-yl)-2-ethyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide

HRID 2135299Notes

Reaction equation

HRID 2135299 reaction equation
[CH2:1]([CH3:2])[N:3]1[S:4](=[O:18])(=[O:19])[c:5]2[c:6]([cH:14][cH:15][cH:16][cH:17]2)[C:7]([OH:13])=[C:8]1[C:9]([O:11][CH3:10])=[O:12].[NH2:20][c:21]1[n:22][c:23]([Cl:27])[cH:24][n:25][cH:26]1.[c:28]1([CH3:29])[c:30]([CH3:31])[cH:32][cH:33][cH:34][cH:35]1>>[CH2:1]([CH3:2])[N:3]1[S:4](=[O:18])(=[O:19])[c:5]2[c:6]([cH:14][cH:15][cH:16][cH:17]2)[C:7]([OH:13])=[C:8]1[C:9](=[O:11])[NH:20][c:21]1[n:22][c:23]([Cl:27])[cH:24][n:25][cH:26]1

Participants

4

Reactant 3

HCID 7237O-XyleneHCID 1184582-Amino-6-ChloropyrazineHCID 54703133methyl 2-ethyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide

Product 1

HCID 54703125N-(6-chloro-pyrazin-2-yl)-2-ethyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide

Sources & evidence

ORD record
ord-638c16e6ed1d4fb88bee241c09dd14a9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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