Acetate → 1-(6-Methylpyridin-2-YL)-2-(quinolin-6-YL)ethanone

HRID 2135408Notes

Reaction equation

HRID 2135408 reaction equation
[C:61]([O-:62])(=[O:63])[CH3:64].[C:66]([O-:67])(=[O:68])[CH3:69].[CH3:12][c:13]1[cH:14][cH:15][cH:16][c:17]([C:19]([CH3:20])=[O:21])[n:18]1.[CH3:50][C:51]([CH3:52])([O-:53])[CH3:54].[CH3:70][C:71](=[O:72])[OH:73].[CH:22]1([P:23]([CH:24]2[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]2)[c:30]2[cH:31][cH:32][cH:33][cH:34][c:35]2-[c:36]2[cH:37][cH:38][cH:39][cH:40][c:41]2[N:42]([CH3:43])[CH3:44])[CH2:45][CH2:46][CH2:47][CH2:48][CH2:49]1.[Cl:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][cH:7][n:8][c:9]2[cH:10][cH:11]1.[K+:55].[O:56]1[CH2:57][CH2:58][CH2:59][CH2:60]1.[Pd+2:65]>>[c:2]1([CH2:20][C:19]([c:17]2[cH:16][cH:15][cH:14][c:13]([CH3:12])[n:18]2)=[O:21])[cH:3][c:4]2[cH:5][cH:6][cH:7][n:8][c:9]2[cH:10][cH:11]1

Participants

10

Reactant 9

HCID 175Acetate2×HCID 176Acetic AcidHCID 813Potassium CationHCID 8028TetrahydrofuranHCID 691636-ChloroquinolineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 1388722-Acetyl-6-methylpyridineHCID 27342172-(Dicyclohexylphosphino)-2'-(dimethylamino)biphenylHCID 45749132-Methylpropan-2-olate

Product 1

HCID 688842031-(6-Methylpyridin-2-YL)-2-(quinolin-6-YL)ethanone

Sources & evidence

ORD record
ord-2658255bbbc740348d40a160d9d8b163
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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