1-[2-(2,2,2-Trifluoroethoxy)phenyl]piperazine → Hydrochloric Acid

HRID 2135427Notes

Reaction equation

HRID 2135427 reaction equation
[F:1][C:2]([CH2:3][O:4][c:5]1[c:6]([N:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)[cH:7][cH:8][cH:9][cH:10]1)([F:17])[F:18].[c:19]1(-[c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[cH:20][c:21]([CH2:25][n:26]2[c:27](=[O:38])[n:28]([CH2:34][CH2:35][CH2:36][Cl:37])[c:29](=[O:33])[c:30]([CH3:32])[cH:31]2)[cH:22][cH:23][cH:24]1>>[ClH:37].[F:1][C:2]([CH2:3][O:4][c:5]1[c:6]([N:11]2[CH2:12][CH2:13][N:14]([CH2:36][CH2:35][CH2:34][n:28]3[c:27](=[O:38])[n:26]([CH2:25][c:21]4[cH:20][c:19](-[c:39]5[cH:40][cH:41][cH:42][cH:43][cH:44]5)[cH:24][cH:23][cH:22]4)[cH:31][c:30]([CH3:32])[c:29]3=[O:33])[CH2:15][CH2:16]2)[cH:7][cH:8][cH:9][cH:10]1)([F:17])[F:18]

Participants

4

Reactant 2

HCID 104915651-[2-(2,2,2-Trifluoroethoxy)phenyl]piperazineHCID 701984331-biphenyl-3-ylmethyl-3-(3-chloropropyl)-5-methyl-2,4(1H,3H)-pyrimidinedione

Product 2

HCID 313Hydrochloric AcidHCID 702023075-Methyl-1-[(3-phenylphenyl)methyl]-3-[3-[4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl]propyl]pyrimidine-2,4-dione

Sources & evidence

ORD record
ord-7bd610f8b204419dbdc600d591b55114
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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