Acetate → 1-(4-Methyl-pyridin-3-yl)-3-(2-pyrrolidin-1-yl-pyridin-4-yl)-imidazolidin-2-one

HRID 213557Notes

Reaction equation

HRID 213557 reaction equation
[CH2:21]1[CH2:22][CH2:23][NH:24][CH2:25]1.[CH3:43][CH2:44][CH2:45][CH2:46][O-:47].[CH3:57][c:58]1[cH:59][cH:60][cH:61][cH:62][cH:63]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([N:8]2[C:9](=[O:20])[N:10]([c:13]3[cH:14][n:15][cH:16][cH:17][c:18]3[CH3:19])[CH2:11][CH2:12]2)[cH:7]1.[K:42].[O-:49][C:50]([CH3:51])=[O:52].[O-:53][C:54]([CH3:55])=[O:56].[Pd+2:48].[c:26]1([C:27]([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)([PH2:34])[CH2:35][CH3:36])[cH:37][cH:38][cH:39][cH:40][cH:41]1>>[c:2]1([N:24]2[CH2:23][CH2:22][CH2:21][CH2:25]2)[n:3][cH:4][cH:5][c:6]([N:8]2[C:9](=[O:20])[N:10]([c:13]3[cH:14][n:15][cH:16][cH:17][c:18]3[CH3:19])[CH2:11][CH2:12]2)[cH:7]1

Participants

9

Reactant 8

HCID 175Acetate2×HCID 1140TolueneHCID 31268PyrrolidineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 5462222PotassiumHCID 12476378Butan-1-olateHCID 21885653Diphenyl phosphinopropaneHCID 49871869Cfg-920

Product 1

HCID 596362441-(4-Methyl-pyridin-3-yl)-3-(2-pyrrolidin-1-yl-pyridin-4-yl)-imidazolidin-2-one

Sources & evidence

ORD record
ord-d73c894de0784e19b61a37c3ff2951c9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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